Inhibition of Carbonic Anhydrase IX Promotes Apoptosis through Intracellular pH Level Alterations in Cervical Cancer Cells

Carbonic anhydrase IX (CAIX) is a hypoxia-related protein that plays a role in proliferation in solid tumours. However, how CAIX increases proliferation and metastasis in solid tumours is unclear. The objective of this study was to investigate how a synthetic CAIX inhibitor triggers apoptosis in the...

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Detalles Bibliográficos
Autores principales: Temiz, Ebru, Koyuncu, Ismail, Durgun, Mustafa, Caglayan, Murat, Gonel, Ataman, Güler, Eray Metin, Kocyigit, Abdurrahim, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201173/
https://www.ncbi.nlm.nih.gov/pubmed/34198834
http://dx.doi.org/10.3390/ijms22116098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201173/
https://www.ncbi.nlm.nih.gov/pubmed/34198834
http://dx.doi.org/10.3390/ijms22116098

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