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Elevated Expression of the RAGE Variant-V in SCLC Mitigates the Effect of Chemotherapeutic Drugs

SIMPLE SUMMARY: Radiomimetic drugs induce extensive genotoxic insults to their target cells. Irreparable DNA damage leaves cells with the choice between a program leading to cell death or senescence, but not DNA repair. Among the challenges of an advanced stage of small cell lung carcinoma (SCLC), t...

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Detalles Bibliográficos
Autores principales: Madhavan, Bindhu K., Han, Zhe, Singh, Bishal, Bordt, Nico, Kaymak, Serap, Bandapalli, Obul Reddy, Kihm, Lars, Shahzad, Khurrum, Isermann, Berend, Herzig, Stephan, Nawroth, Peter, Kumar, Varun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201239/
https://www.ncbi.nlm.nih.gov/pubmed/34200336
http://dx.doi.org/10.3390/cancers13112843