In Silico and In Vitro Analyses Validate Human MicroRNAs Targeting the SARS-CoV-2 3′-UTR

COVID-19 pandemic is caused by betacoronavirus SARS-CoV-2. The genome of this virus is composed of a single strand of RNA with 5′ and 3′-UTR flanking a region of protein-coding ORFs closely resembling cells’ mRNAs. MicroRNAs are endogenous post-transcriptional regulators that target mRNA to modulate...

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Detalles Bibliográficos
Autores principales: Barreda-Manso, María Asunción, Nieto-Díaz, Manuel, Soto, Altea, Muñoz-Galdeano, Teresa, Reigada, David, Maza, Rodrigo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201247/
https://www.ncbi.nlm.nih.gov/pubmed/34198800
http://dx.doi.org/10.3390/ijms22116094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201247/
https://www.ncbi.nlm.nih.gov/pubmed/34198800
http://dx.doi.org/10.3390/ijms22116094

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