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Loss of Nnt Increases Expression of Oxidative Phosphorylation Complexes in C57BL/6J Hearts

Nicotinamide nucleotide transhydrogenase (NNT) is a proton pump in the inner mitochondrial membrane that generates reducing equivalents in the form of NAPDH, which can be used for anabolic pathways or to remove reactive oxygen species (ROS). A number of studies have linked NNT dysfunction to cardiom...

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Detalles Bibliográficos
Autores principales: Williams, Jack L., Hall, Charlotte L., Meimaridou, Eirini, Metherell, Lou A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201288/
https://www.ncbi.nlm.nih.gov/pubmed/34198873
http://dx.doi.org/10.3390/ijms22116101