Overexpression of miR-124 in Motor Neurons Plays a Key Role in ALS Pathological Processes

miRNA(miR)-124 is an important regulator of neurogenesis, but its upregulation in SOD1G93A motor neurons (mSOD1 MNs) was shown to associate with neurodegeneration and microglia activation. We used pre-miR-124 in wild-type (WT) MNs and anti-miR-124 in mSOD1 MNs to characterize the miR-124 pathologica...

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Detalles Bibliográficos
Autores principales: Vaz, Ana Rita, Vizinha, Daniela, Morais, Hermes, Colaço, Ana Rita, Loch-Neckel, Gecioni, Barbosa, Marta, Brites, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201298/
https://www.ncbi.nlm.nih.gov/pubmed/34200161
http://dx.doi.org/10.3390/ijms22116128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201298/
https://www.ncbi.nlm.nih.gov/pubmed/34200161
http://dx.doi.org/10.3390/ijms22116128

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