Disruption of Tfh:B Cell Interactions Prevents Antibody-Mediated Rejection in a Kidney Transplant Model in Rats: Impact of Calcineurin Inhibitor Dose

We aimed to investigate the mechanisms of humoral immune activation in ABMR using a MHC-mismatched rat kidney transplant model. We applied low dose cyclosporine A (loCNI) to allow donor-specific antibody (DSA) formation and rejection and high dose cyclosporine A (hiCNI) for non-rejection. DSA and le...

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Detalles Bibliográficos
Autores principales: Steines, Louisa, Poth, Helen, Schuster, Antonia, Amann, Kerstin, Banas, Bernhard, Bergler, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201497/
https://www.ncbi.nlm.nih.gov/pubmed/34135891
http://dx.doi.org/10.3389/fimmu.2021.657894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201497/
https://www.ncbi.nlm.nih.gov/pubmed/34135891
http://dx.doi.org/10.3389/fimmu.2021.657894

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