Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation

Parkinson’s disease is a neurodegenerative disorder in which activated microglia may appear prior to motor symptoms, but the specific therapeutic mechanisms remain unclear. This study investigated the potential effects of Edaravone (EDA) on M1/M2 polarization of microglia in rats with dopaminergic n...

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Detalles Bibliográficos
Autores principales: Li, Jiping, Dai, Xinping, zhou, Liuyi, Li, Xinxiu, Pan, Dongxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201503/
https://www.ncbi.nlm.nih.gov/pubmed/34135761
http://dx.doi.org/10.3389/fphar.2021.691773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201503/
https://www.ncbi.nlm.nih.gov/pubmed/34135761
http://dx.doi.org/10.3389/fphar.2021.691773

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