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Calycosin-loaded nanoliposomes as potential nanoplatforms for treatment of diabetic nephropathy through regulation of mitochondrial respiratory function

BACKGROUNDS: One of the most common complications in diabetic nephropathy is generation of high levels of ROS which can be regulated by herbal antioxidants. However, polyphenols like calycosin, the bioactive compound of Radix astragali suffer from low solubility and poor bioavailability. METHODS: Th...

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Detalles Bibliográficos
Autores principales: Huang, Chunrong, Xue, Lian-Fang, Hu, Bo, Liu, Huan-Huan, Huang, Si-Bo, Khan, Suliman, Meng, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201677/
https://www.ncbi.nlm.nih.gov/pubmed/34120609
http://dx.doi.org/10.1186/s12951-021-00917-1