Increased peak detection accuracy in over-dispersed ChIP-seq data with supervised segmentation models

BACKGROUND: Histone modification constitutes a basic mechanism for the genetic regulation of gene expression. In early 2000s, a powerful technique has emerged that couples chromatin immunoprecipitation with high-throughput sequencing (ChIP-seq). This technique provides a direct survey of the DNA reg...

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Detalles Bibliográficos
Autores principales: Liehrmann, Arnaud, Rigaill, Guillem, Hocking, Toby Dylan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201703/
https://www.ncbi.nlm.nih.gov/pubmed/34126932
http://dx.doi.org/10.1186/s12859-021-04221-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201703/
https://www.ncbi.nlm.nih.gov/pubmed/34126932
http://dx.doi.org/10.1186/s12859-021-04221-5

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