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Electric signals counterbalanced posterior vs anterior PTEN signaling in directed migration of Dictyostelium
BACKGROUND: Cells show directed migration response to electric signals, namely electrotaxis or galvanotaxis. PI3K and PTEN jointly play counterbalancing roles in this event via a bilateral regulation of PIP3 signaling. PI3K has been proved essential in anterior signaling of electrotaxing cells, whil...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201722/ https://www.ncbi.nlm.nih.gov/pubmed/34127068 http://dx.doi.org/10.1186/s13578-021-00580-x |