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Electric signals counterbalanced posterior vs anterior PTEN signaling in directed migration of Dictyostelium

BACKGROUND: Cells show directed migration response to electric signals, namely electrotaxis or galvanotaxis. PI3K and PTEN jointly play counterbalancing roles in this event via a bilateral regulation of PIP3 signaling. PI3K has been proved essential in anterior signaling of electrotaxing cells, whil...

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Detalles Bibliográficos
Autores principales: Song, Bing, Gu, Yu, Jiang, Wenkai, Li, Ying, Ayre, Wayne Nishio, Liu, Zhipeng, Yin, Tao, Janetopoulos, Christopher, Iijima, Miho, Devreotes, Peter, Zhao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201722/
https://www.ncbi.nlm.nih.gov/pubmed/34127068
http://dx.doi.org/10.1186/s13578-021-00580-x