De novo design of a pH-triggered self-assembled β-hairpin nanopeptide with the dual biological functions for antibacterial and entrapment

BACKGROUND: Acid-tolerant enteric pathogens can evade small intestinal acid barriers, colonize and infect the intestinal tract. However, broad-spectrum antibiotics are not the best therapeutic strategy because of the disruption of intestinal flora caused by its indiscriminate antimicrobial activity...

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Detalles Bibliográficos
Autores principales: Li, Qiuke, Li, Jinze, Yu, Weikang, Wang, Zhihua, Li, Jiawei, Feng, Xingjun, Wang, Jiajun, Shan, Anshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201815/
https://www.ncbi.nlm.nih.gov/pubmed/34127004
http://dx.doi.org/10.1186/s12951-021-00927-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201815/
https://www.ncbi.nlm.nih.gov/pubmed/34127004
http://dx.doi.org/10.1186/s12951-021-00927-z

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