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De novo design of a pH-triggered self-assembled β-hairpin nanopeptide with the dual biological functions for antibacterial and entrapment
BACKGROUND: Acid-tolerant enteric pathogens can evade small intestinal acid barriers, colonize and infect the intestinal tract. However, broad-spectrum antibiotics are not the best therapeutic strategy because of the disruption of intestinal flora caused by its indiscriminate antimicrobial activity...
Autores principales: | Li, Qiuke, Li, Jinze, Yu, Weikang, Wang, Zhihua, Li, Jiawei, Feng, Xingjun, Wang, Jiajun, Shan, Anshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201815/ https://www.ncbi.nlm.nih.gov/pubmed/34127004 http://dx.doi.org/10.1186/s12951-021-00927-z |
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