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LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions

Regulation of cell volume is essential for tissue homeostasis and cell viability. In response to hypertonic stress, cells need rapid electrolyte influx to compensate water loss and to prevent cell death in a process known as regulatory volume increase (RVI). However, the molecular component able to...

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Detalles Bibliográficos
Autores principales: Serra, Selma A., Stojakovic, Predrag, Amat, Ramon, Rubio-Moscardo, Fanny, Latorre, Pablo, Seisenbacher, Gerhard, Canadell, David, Böttcher, René, Aregger, Michael, Moffat, Jason, de Nadal, Eulàlia, Valverde, Miguel A., Posas, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201826/
https://www.ncbi.nlm.nih.gov/pubmed/34083438
http://dx.doi.org/10.1073/pnas.2025013118