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LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions
Regulation of cell volume is essential for tissue homeostasis and cell viability. In response to hypertonic stress, cells need rapid electrolyte influx to compensate water loss and to prevent cell death in a process known as regulatory volume increase (RVI). However, the molecular component able to...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201826/ https://www.ncbi.nlm.nih.gov/pubmed/34083438 http://dx.doi.org/10.1073/pnas.2025013118 |