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Does the epigenetic clock GrimAge predict mortality independent of genetic influences: an 18 year follow-up study in older female twin pairs

BACKGROUND: Epigenetic clocks are based on DNA methylation (DNAm). It has been suggested that these clocks are useable markers of biological aging and premature mortality. Because genetic factors explain variations in both epigenetic aging and mortality, this association could also be explained by s...

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Detalles Bibliográficos
Autores principales: Tiina, Föhr, Katja, Waller, Anne, Viljanen, Riikka, Sanchez, Miina, Ollikainen, Taina, Rantanen, Jaakko, Kaprio, Sillanpää, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201844/
https://www.ncbi.nlm.nih.gov/pubmed/34120642
http://dx.doi.org/10.1186/s13148-021-01112-7