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Novel combined variants of WT1 and TET2 in a refractory and recurrent AML patient

BACKGROUND: Somatic mutations in Wilms' tumor 1 (WT1) and tet methylcytosine dioxygenase 2 (TET2) genes were separately perceived as contributors to hematopoietic disorders and usually thought to have a mutually exclusive effect in acute myeloid leukemia (AML). However, we found novel WT1 and T...

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Detalles Bibliográficos
Autores principales: Ma, Qiang, Guo, Yixian, Lan, Xiaoxi, Wang, Guoxiang, Sun, Wanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201863/
https://www.ncbi.nlm.nih.gov/pubmed/34120595
http://dx.doi.org/10.1186/s12920-021-01002-0