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Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes

BACKGROUND: Canonical nonsense-mediated decay (NMD) is an important splicing-dependent process for mRNA surveillance in mammals. However, processed pseudogenes are not able to trigger NMD due to their lack of introns. It is largely unknown whether they have evolved other surveillance mechanisms. RES...

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Detalles Bibliográficos
Autores principales: Tan, Liqiang, Cheng, Weisheng, Liu, Fang, Wang, Dan Ohtan, Wu, Linwei, Cao, Nan, Wang, Jinkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201931/
https://www.ncbi.nlm.nih.gov/pubmed/34120636
http://dx.doi.org/10.1186/s13059-021-02402-2