Integrative Ranking of Enhancer Networks Facilitates the Discovery of Epigenetic Markers in Cancer

Regulation of gene expression through multiple epigenetic components is a highly combinatorial process. Alterations in any of these layers, as is commonly found in cancer diseases, can lead to a cascade of downstream effects on tumor suppressor or oncogenes. Hence, deciphering the effects of epigene...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Wu, Yonghe, Vorberg, Tim, Eils, Roland, Herrmann, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201988/
https://www.ncbi.nlm.nih.gov/pubmed/34135941
http://dx.doi.org/10.3389/fgene.2021.664654