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TagSNP approach for HLA risk allele genotyping of Saudi celiac disease patients: effectiveness and pitfalls

Background: Celiac disease (CD) is a genetically complex autoimmune disease which is triggered by dietary gluten. Human leukocyte antigen (HLA) class II genes are known to act as high-risk markers for CD, where >95% of CD patients carry (HLA), DQ2 and/or DQ8 alleles. Therefore, the present study...

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Detalles Bibliográficos
Autores principales: Baaqeel, Reham H., Banaganapalli, Babajan, Al Mahdi, Hadiah Bassam, Salama, Mohammed A., Alhussaini, Bakr H., Alaifan, Meshari A., Bin-Taleb, Yagoub, Shaik, Noor Ahmad, Al-Aama, Jumana Yousuf, Elango, Ramu, Saadah, Omar I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202064/
https://www.ncbi.nlm.nih.gov/pubmed/34042155
http://dx.doi.org/10.1042/BSR20210509