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Mesoporous silica nanoparticles inflame tumors to overcome anti-PD-1 resistance through TLR4-NFκB axis

BACKGROUND: The clinical benefits of antiprogrammed cell death protein 1 (PD-1) therapy are compromised by resistance in immunologically cold tumors. Convergence of immunotherapy and bioengineering is potential to overcome the resistance. Mesoporous silica nanoparticles (MSNs) are considered the mos...

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Detalles Bibliográficos
Autores principales: Sun, Mayu, Gu, Pengfei, Yang, Yang, Yu, Luodan, Jiang, Zheshun, Li, Jingquan, Le, Yingying, Chen, Yu, Ba, Qian, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202116/
https://www.ncbi.nlm.nih.gov/pubmed/34117115
http://dx.doi.org/10.1136/jitc-2021-002508