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Diffusion models reveal white matter microstructural changes with ageing, pathology and cognition

White matter microstructure undergoes progressive changes during the lifespan, but the neurobiological underpinnings related to ageing and disease remains unclear. We used an advanced diffusion MRI, Neurite Orientation Dispersion and Density Imaging, to investigate the microstructural alterations du...

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Detalles Bibliográficos
Autores principales: Raghavan, Sheelakumari, Reid, Robert I, Przybelski, Scott A, Lesnick, Timothy G, Graff-Radford, Jonathan, Schwarz, Christopher G, Knopman, David S, Mielke, Michelle M, Machulda, Mary M, Petersen, Ronald C, Jack, Clifford R, Vemuri, Prashanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202149/
https://www.ncbi.nlm.nih.gov/pubmed/34136811
http://dx.doi.org/10.1093/braincomms/fcab106