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GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells

In addition to driving specific gene expression profiles, transcriptional regulators are becoming increasingly recognized for their capacity to modulate chromatin structure. GATA6 is essential for the formation of definitive endoderm; however, the molecular basis defining the importance of GATA6 to...

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Detalles Bibliográficos
Autores principales: Heslop, James A., Pournasr, Behshad, Liu, Jui-Tung, Duncan, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202205/
https://www.ncbi.nlm.nih.gov/pubmed/34010638
http://dx.doi.org/10.1016/j.celrep.2021.109145