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ChIP-seq protocol for sperm cells and embryos to assess environmental impacts and epigenetic inheritance

In the field of epigenetic inheritance, delineating molecular mechanisms implicated in the transfer of paternal environmental conditions to descendants has been elusive. This protocol details how to track sperm chromatin intergenerationally. We describe mouse model design to probe chromatin states i...

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Detalles Bibliográficos
Autores principales: Lismer, Ariane, Lambrot, Romain, Lafleur, Christine, Dumeaux, Vanessa, Kimmins, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202352/
https://www.ncbi.nlm.nih.gov/pubmed/34159325
http://dx.doi.org/10.1016/j.xpro.2021.100602