Single-Cell Trajectory Inference Guided Enhancement of Thyroid Maturation In Vitro Using TGF-Beta Inhibition

The thyroid gland regulates metabolism and growth via secretion of thyroid hormones by thyroid follicular cells (TFCs). Loss of TFCs, by cellular dysfunction, autoimmune destruction or surgical resection, underlies hypothyroidism. Recovery of thyroid hormone levels by transplantation of mature TFCs...

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Detalles Bibliográficos
Autores principales: Romitti, Mírian, Eski, Sema Elif, Fonseca, Barbara Faria, Gillotay, Pierre, Singh, Sumeet Pal, Costagliola, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202408/
https://www.ncbi.nlm.nih.gov/pubmed/34135860
http://dx.doi.org/10.3389/fendo.2021.657195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202408/
https://www.ncbi.nlm.nih.gov/pubmed/34135860
http://dx.doi.org/10.3389/fendo.2021.657195

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