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Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

While inhibition of T cell co-inhibitory receptors has revolutionized cancer therapy, the mechanisms governing their expression on human T cells have not been elucidated. Type 1 interferon (IFN-I) modulates T cell immunity in viral infection, autoimmunity, and cancer, and may facilitate induction of...

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Detalles Bibliográficos
Autores principales: Hafler, David, Sumida, Tomokazu, Dulberg, Shai, Schupp, Jonas, Stillwell, Helen, Axisa, Pierre-Paul, Comi, Michela, Lincoln, Matthew, Unterman, Avraham, Kaminski, Naftali, Madi, Asaf, Kuchroo, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202434/
https://www.ncbi.nlm.nih.gov/pubmed/34127967
http://dx.doi.org/10.21203/rs.3.rs-133494/v1