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Setting the Beta-Lactam Therapeutic Range for Critically Ill Patients: Is There a Floor or Even a Ceiling?

OBJECTIVES: Beta-lactam antibiotics exhibit high interindividual variability in drug concentrations in patients with critical illness which led to an interest in the use of therapeutic drug monitoring to improve effectiveness and safety. To implement therapeutic drug monitoring, it is necessary to d...

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Detalles Bibliográficos
Autores principales: Barreto, Erin F., Webb, Andrew J., Pais, Gwendolyn M., Rule, Andrew D., Jannetto, Paul J., Scheetz, Marc H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202642/
https://www.ncbi.nlm.nih.gov/pubmed/34136822
http://dx.doi.org/10.1097/CCE.0000000000000446