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Reaction of Tertiary 2‐Chloroketones with Cyanide Ions: Application to 3‐Chloroquinolinediones

3‐Chloroquinoline‐2,4‐diones react with cyanide ions in dimethyl formamide to give 3‐cyanoquinoline‐2,4‐diones in small yields due to the strong hindrance of the substituent at the C‐3 atom. Good yields can be achieved if the substituent at this position is the methyl group. In the methanol solution...

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Detalles Bibliográficos
Autores principales: Klásek, Antonín, Kafka, Stanislav, Rudolf, Ondřej, Lyčka, Antonín, Rouchal, Michal, Bednář, Lukáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202728/
https://www.ncbi.nlm.nih.gov/pubmed/34126002
http://dx.doi.org/10.1002/open.202100024