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Reaction of Tertiary 2‐Chloroketones with Cyanide Ions: Application to 3‐Chloroquinolinediones
3‐Chloroquinoline‐2,4‐diones react with cyanide ions in dimethyl formamide to give 3‐cyanoquinoline‐2,4‐diones in small yields due to the strong hindrance of the substituent at the C‐3 atom. Good yields can be achieved if the substituent at this position is the methyl group. In the methanol solution...
Autores principales: | Klásek, Antonín, Kafka, Stanislav, Rudolf, Ondřej, Lyčka, Antonín, Rouchal, Michal, Bednář, Lukáš |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202728/ https://www.ncbi.nlm.nih.gov/pubmed/34126002 http://dx.doi.org/10.1002/open.202100024 |
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