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Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids
The exocrine pancreas, consisting of ducts and acini, is the site of origin of pancreatitis and pancreatic ductal adenocarcinoma (PDAC). Our understanding of the genesis and progression of human pancreatic diseases, including PDAC, is limited because of challenges in maintaining human acinar and duc...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202734/ https://www.ncbi.nlm.nih.gov/pubmed/33915081 http://dx.doi.org/10.1016/j.stem.2021.03.022 |