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Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids

The exocrine pancreas, consisting of ducts and acini, is the site of origin of pancreatitis and pancreatic ductal adenocarcinoma (PDAC). Our understanding of the genesis and progression of human pancreatic diseases, including PDAC, is limited because of challenges in maintaining human acinar and duc...

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Detalles Bibliográficos
Autores principales: Huang, Ling, Desai, Ridhdhi, Conrad, Daniel N., Leite, Nayara C., Akshinthala, Dipikaa, Lim, Christine Maria, Gonzalez, Raul, Muthuswamy, Lakshmi B., Gartner, Zev, Muthuswamy, Senthil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202734/
https://www.ncbi.nlm.nih.gov/pubmed/33915081
http://dx.doi.org/10.1016/j.stem.2021.03.022