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S100B gene polymorphisms are associated with the S100B level and Alzheimer’s disease risk by altering the miRNA binding capacity

To examine the role of S100B in genetic susceptibility to Alzheimer’s disease (AD), we conducted a case-control study to analyze four polymorphism loci (rs2839364, rs1051169, rs2300403, and rs9722) of the S100B gene and AD risk. We found an independent increased risk of AD in ApoE ε4(-) subjects car...

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Detalles Bibliográficos
Autores principales: Wang, Jiafeng, Zhou, Yulan, Yang, Yixia, Gao, Xiang, Liu, Zhibin, Hong, Guanhao, Yao, Lifen, Yin, Jingwen, Gu, Xuefeng, Li, Keshen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202836/
https://www.ncbi.nlm.nih.gov/pubmed/33982673
http://dx.doi.org/10.18632/aging.203005