Systemic NF-κB-mediated inflammation promotes an aging phenotype in skeletal stem/progenitor cells

Aging tissues undergo a progressive decline in regenerative potential. This decline in regenerative responsiveness has been attributed to changes in tissue-specific stem cells and their niches. In bone, aged skeletal stem/progenitor cell dysfunction is characterized by decreased frequency and impair...

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Detalles Bibliográficos
Autores principales: Josephson, Anne Marie, Leclerc, Kevin, Remark, Lindsey H., Lopeź, Emma Muiños, Leucht, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202837/
https://www.ncbi.nlm.nih.gov/pubmed/34035186
http://dx.doi.org/10.18632/aging.203083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202837/
https://www.ncbi.nlm.nih.gov/pubmed/34035186
http://dx.doi.org/10.18632/aging.203083

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