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Chronic alcohol exposure promotes HCC stemness and metastasis through β-catenin/miR-22-3p/TET2 axis

Hepatocellular Carcinoma (HCC) patients usually have a high rate of relapse and metastasis. Alcohol, a risk factor for HCC, promotes the aggressiveness of HCC. However, the basic mechanism is still unclear. We used HCC cells and an orthotopic liver tumor model of HCC-LM3 cells for BALB/C nude mice t...

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Detalles Bibliográficos
Autores principales: Chen, Danlei, Yan, Yan, Wang, Xinyi, Li, Suzhi, Liu, Yan, Yu, Dandan, He, Yongjing, Deng, Ruiqing, Liu, Yakun, Xu, Mei, Luo, Jia, Gao, Hongjun, Wang, Siying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202861/
https://www.ncbi.nlm.nih.gov/pubmed/34019487
http://dx.doi.org/10.18632/aging.203059