Cdkn1a transcript variant 2 is a marker of aging and cellular senescence

Cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16(Ink4a) and p21(Cip1/Waf1). In mice, the p21(Cip1/Waf1) encoding locus, Cdkn1a, is known to generate two transcripts that produce i...

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Detalles Bibliográficos
Autores principales: López-Domínguez, José Alberto, Rodríguez-López, Sandra, Ahumada-Castro, Ulises, Desprez, Pierre-Yves, Konovalenko, Maria, Laberge, Remi-Martin, Cárdenas, César, Villalba, José Manuel, Campisi, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202863/
https://www.ncbi.nlm.nih.gov/pubmed/34035185
http://dx.doi.org/10.18632/aging.203110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202863/
https://www.ncbi.nlm.nih.gov/pubmed/34035185
http://dx.doi.org/10.18632/aging.203110

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