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microRNA-1246-containing extracellular vesicles from acute myeloid leukemia cells promote the survival of leukemia stem cells via the LRIG1-meditated STAT3 pathway

Cancer cells-secreted extracellular vesicles (EVs) have emerged as important mediators of intercellular communication in local and distant microenvironment. Our initial GEO database analysis identified the presence of differentially-expressed microRNA-1246 (miR-1246) in acute myeloid leukemia (AML)...

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Detalles Bibliográficos
Autores principales: Chen, Lijuan, Guo, Zhi, Zhou, Yongming, Ni, Jian, Zhu, Jianhua, Fan, Xu, Chen, Xuexing, Liu, Yiling, Li, Ziping, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202884/
https://www.ncbi.nlm.nih.gov/pubmed/33893245
http://dx.doi.org/10.18632/aging.202893