Sustained viremia suppression by SHIV(SF162P3CN)-recalled effector-memory CD8(+) T cells after PD1-based vaccination

HIV-1 functional cure requires sustained viral suppression without antiretroviral therapy. While effector-memory CD8(+) T lymphocytes are essential for viremia control, few vaccines elicit such cellular immunity that could be potently recalled upon viral infection. Here, we investigated a program de...

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Detalles Bibliográficos
Autores principales: Wong, Yik Chun, Liu, Wan, Yim, Lok Yan, Li, Xin, Wang, Hui, Yue, Ming, Niu, Mengyue, Cheng, Lin, Ling, Lijun, Du, Yanhua, Chen, Samantha M. Y., Cheung, Ka-Wai, Wang, Haibo, Tang, Xian, Tang, Jiansong, Zhang, Haoji, Song, Youqiang, Chakrabarti, Lisa A., Chen, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202916/
https://www.ncbi.nlm.nih.gov/pubmed/34125864
http://dx.doi.org/10.1371/journal.ppat.1009647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202916/
https://www.ncbi.nlm.nih.gov/pubmed/34125864
http://dx.doi.org/10.1371/journal.ppat.1009647

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