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Sustained viremia suppression by SHIV(SF162P3CN)-recalled effector-memory CD8(+) T cells after PD1-based vaccination
HIV-1 functional cure requires sustained viral suppression without antiretroviral therapy. While effector-memory CD8(+) T lymphocytes are essential for viremia control, few vaccines elicit such cellular immunity that could be potently recalled upon viral infection. Here, we investigated a program de...
Autores principales: | Wong, Yik Chun, Liu, Wan, Yim, Lok Yan, Li, Xin, Wang, Hui, Yue, Ming, Niu, Mengyue, Cheng, Lin, Ling, Lijun, Du, Yanhua, Chen, Samantha M. Y., Cheung, Ka-Wai, Wang, Haibo, Tang, Xian, Tang, Jiansong, Zhang, Haoji, Song, Youqiang, Chakrabarti, Lisa A., Chen, Zhiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202916/ https://www.ncbi.nlm.nih.gov/pubmed/34125864 http://dx.doi.org/10.1371/journal.ppat.1009647 |
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