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The effects of biological aging on global DNA methylation, histone modification, and epigenetic modifiers in the mouse germinal vesicle stage oocyte

A cultural trend in developed countries is favoring a delay in maternal age at first childbirth. In mammals fertility and chronological age show an inverse correlation. Oocyte quality is a contributing factor to this multifactorial phenomenon that may be influenced by age-related changes in the oocy...

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Detalles Bibliográficos
Autores principales: Marshall, Kira Lynn, Wang, Juanbin, Ji, Tieming, Rivera, Rocío Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Reprodução Animal 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203117/
https://www.ncbi.nlm.nih.gov/pubmed/34221140
http://dx.doi.org/10.21451/1984-3143-AR2018-0087