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G9a Regulates Cell Sensitivity to Radiotherapy via Histone H3 Lysine 9 Trimethylation and CCDC8 in Lung Cancer

PURPOSE: To investigate the role and underlying mechanism of G9a and CCDC8 in lung cancer radioresistance. METHODS: Western blotting assays were used for G9a, CCDC8, H3K9me3 expression detection. MTT assays and clone formation assays were used for measuring cell proliferation activities. Flow cytome...

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Detalles Bibliográficos
Autores principales: Li, Yunfen, Chen, Zhengting, Cao, Ke, Zhang, Lan, Ma, Yuhui, Yu, Shuhui, Jin, Hanyu, Liu, Xiaoling, Li, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203200/
https://www.ncbi.nlm.nih.gov/pubmed/34140780
http://dx.doi.org/10.2147/OTT.S296937