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A Precision Medicine Approach to Treating Alzheimer’s Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials

BACKGROUND: The REFLECT trials were conducted to examine the treatment of mild-to-moderate Alzheimer’s disease utilizing a peroxisome proliferator-activated receptor gamma agonist. OBJECTIVE: To generate a predictive biomarker indicative of positive treatment response using samples from the previous...

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Detalles Bibliográficos
Autores principales: O’Bryant, Sid E., Zhang, Fan, Petersen, Melissa, Johnson, Leigh, Hall, James, Rissman, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203239/
https://www.ncbi.nlm.nih.gov/pubmed/33814447
http://dx.doi.org/10.3233/JAD-201610