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Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer’s Disease and Inflammation at the Pre- and Early Stages of Dementia

BACKGROUND: Understanding how dysregulation in lipid metabolism relates to the severity of Alzheimer‘s disease (AD) pathology might be critical in developing effective treatments. OBJECTIVE: To identify lipid species in cerebrospinal fluid (CSF) associated with signature AD pathology and to explore...

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Detalles Bibliográficos
Autores principales: Teitsdottir, Unnur D., Halldorsson, Skarphedinn, Rolfsson, Ottar, Lund, Sigrun H., Jonsdottir, Maria K., Snaedal, Jon, Petersen, Petur H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203241/
https://www.ncbi.nlm.nih.gov/pubmed/33814423
http://dx.doi.org/10.3233/JAD-200964