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Zebrafish Chromosome 14 Gene Differential Expression in the fmr1(hu2787) Model of Fragile X Syndrome

Zebrafish represent a valuable model for investigating the molecular and cellular basis of Fragile X syndrome (FXS). Reduced expression of the zebrafish FMR1 orthologous gene, fmr1, causes developmental and behavioural phenotypes related to FXS. Zebrafish homozygous for the hu2787 non-sense mutation...

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Detalles Bibliográficos
Autores principales: Barthelson, Karissa, Baer, Lachlan, Dong, Yang, Hand, Melanie, Pujic, Zac, Newman, Morgan, Goodhill, Geoffrey J., Richards, Robert I., Pederson, Stephen M., Lardelli, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203322/
https://www.ncbi.nlm.nih.gov/pubmed/34135935
http://dx.doi.org/10.3389/fgene.2021.625466