CRISPR-Cas9 Editing of Human Histone Deubiquitinase Gene USP16 in Human Monocytic Leukemia Cell Line THP-1

USP16 is a histone deubiquitinase which facilitates G2/M transition during the cell cycle, regulates DNA damage repair and contributes to inducible gene expression. We mutated the USP16 gene in a high differentiation clone of the acute monocytic leukemia cell line THP-1 using the CRISPR-Cas9 system...

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Detalles Bibliográficos
Autores principales: Gažová, Iveta, Lefevre, Lucas, Bush, Stephen J., Rojo, Rocio, Hume, David A., Lengeling, Andreas, Summers, Kim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203323/
https://www.ncbi.nlm.nih.gov/pubmed/34136489
http://dx.doi.org/10.3389/fcell.2021.679544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203323/
https://www.ncbi.nlm.nih.gov/pubmed/34136489
http://dx.doi.org/10.3389/fcell.2021.679544

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