Identification of a defined linear epitope in the OspA protein of the Lyme disease spirochetes that elicits bactericidal antibody responses: Implications for vaccine development

The lipoprotein OspA is produced by the Lyme disease spirochetes primarily in unfed ticks. OspA production is down-regulated by the blood meal and it is not produced in mammals except for possible transient production during late stage infection in patients with Lyme arthritis. Vaccination with OspA...

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Detalles Bibliográficos
Autores principales: Izac, Jerilyn R., Oliver, Lee D., Earnhart, Christopher G., Marconi, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203411/
https://www.ncbi.nlm.nih.gov/pubmed/28479174
http://dx.doi.org/10.1016/j.vaccine.2017.04.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203411/
https://www.ncbi.nlm.nih.gov/pubmed/28479174
http://dx.doi.org/10.1016/j.vaccine.2017.04.079

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