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Caldesmon ablation in mice causes umbilical herniation and alters contractility of fetal urinary bladder smooth muscle

The actin-, myosin-, and calmodulin-binding protein caldesmon (CaD) is expressed in two splice isoforms: h-CaD, which is an integral part of the actomyosin domain of smooth muscle cells, and l-CaD, which is widely expressed and is involved in many cellular functions. Despite extensive research for m...

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Detalles Bibliográficos
Autores principales: Pütz, Sandra, Barthel, Lisa Sophie, Frohn, Marina, Metzler, Doris, Barham, Mohammed, Pryymachuk, Galyna, Trunschke, Oliver, Lubomirov, Lubomir T., Hescheler, Jürgen, Chalovich, Joseph M., Neiss, Wolfram F., Koch, Manuel, Schroeter, Mechthild M., Pfitzer, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203487/
https://www.ncbi.nlm.nih.gov/pubmed/34115104
http://dx.doi.org/10.1085/jgp.202012776