TCR-like CARs and TCR-CARs targeting neoepitopes: an emerging potential

Neoepitopes or neoantigens are a spectrum of unique mutations presented in a particular patient’s tumor. Neoepitope-based adoptive therapies have the potential of tumor eradication without undue damaging effect on normal tissues. In this context, methods based on the T cell receptor (TCR) engineerin...

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Detalles Bibliográficos
Autores principales: Poorebrahim, Mansour, Mohammadkhani, Niloufar, Mahmoudi, Reza, Gholizadeh, Monireh, Fakhr, Elham, Cid-Arregui, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203496/
https://www.ncbi.nlm.nih.gov/pubmed/33654227
http://dx.doi.org/10.1038/s41417-021-00307-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203496/
https://www.ncbi.nlm.nih.gov/pubmed/33654227
http://dx.doi.org/10.1038/s41417-021-00307-7

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