Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse

Calcineurin inhibitors, such as Cyclosporin (CsA), are the mainstay of anti-rejection therapy in solid organ transplants but can paradoxically induce progressive nephropathy characterised by renal dysfunction and interstitial fibrosis. Lysyl oxidases (LOXs), a group of enzymes that catalyse extracel...

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Detalles Bibliográficos
Autores principales: Nguyen, Long T., Saad, Sonia, Shi, Ying, Wang, Rosy, Chou, Angela S. Y., Gill, Anthony, Yao, Yimin, Jarolimek, Wolfgang, Pollock, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203624/
https://www.ncbi.nlm.nih.gov/pubmed/34127702
http://dx.doi.org/10.1038/s41598-021-91772-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203624/
https://www.ncbi.nlm.nih.gov/pubmed/34127702
http://dx.doi.org/10.1038/s41598-021-91772-5

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