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Deletion of the lactoperoxidase gene causes multisystem inflammation and tumors in mice

Strongly oxidative H(2)O(2) is biologically important, but if uncontrolled, would lead to tissue injuries. Lactoperoxidase (LPO) catalyzes the redox reaction of reducing highly reactive H(2)O(2) to H(2)O while oxidizing thiocyanate (SCN(−)) to relatively tissue-innocuous hypothiocyanite (OSCN(−)). S...

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Detalles Bibliográficos
Autores principales: Yamakaze, Jayden, Lu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203638/
https://www.ncbi.nlm.nih.gov/pubmed/34127712
http://dx.doi.org/10.1038/s41598-021-91745-8