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Deletion of the lactoperoxidase gene causes multisystem inflammation and tumors in mice
Strongly oxidative H(2)O(2) is biologically important, but if uncontrolled, would lead to tissue injuries. Lactoperoxidase (LPO) catalyzes the redox reaction of reducing highly reactive H(2)O(2) to H(2)O while oxidizing thiocyanate (SCN(−)) to relatively tissue-innocuous hypothiocyanite (OSCN(−)). S...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203638/ https://www.ncbi.nlm.nih.gov/pubmed/34127712 http://dx.doi.org/10.1038/s41598-021-91745-8 |