Pseudogene ACTBP2 increases blood–brain barrier permeability by promoting KHDRBS2 transcription through recruitment of KMT2D/WDR5 in Aβ(1–)(42) microenvironment

The blood–brain barrier (BBB) has a vital role in maintaining the homeostasis of the central nervous system (CNS). Changes in the structure and function of BBB can accelerate Alzheimer’s disease (AD) development. β-Amyloid (Aβ) deposition is the major pathological event of AD. We elucidated the func...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Qianshuo, Liu, Xiaobai, Zhao, Defeng, Ruan, Xuelei, Su, Rui, Shang, Xiuli, Wang, Di, Yang, Chunqing, Xue, Yixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203645/
https://www.ncbi.nlm.nih.gov/pubmed/34127651
http://dx.doi.org/10.1038/s41420-021-00531-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203645/
https://www.ncbi.nlm.nih.gov/pubmed/34127651
http://dx.doi.org/10.1038/s41420-021-00531-y

Ejemplares similares