A genome-wide portrait of pervasive drug contaminants

Using a validated yeast chemogenomic platform, we characterized the genome-wide effects of several pharmaceutical contaminants, including three N-nitrosamines (NDMA, NDEA and NMBA), two related compounds (DMF and 4NQO) and several of their metabolites. A collection of 4800 non-essential homozygous d...

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Detalles Bibliográficos
Autores principales: Ogbede, Joseph Uche, Giaever, Guri, Nislow, Corey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203678/
https://www.ncbi.nlm.nih.gov/pubmed/34127714
http://dx.doi.org/10.1038/s41598-021-91792-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203678/
https://www.ncbi.nlm.nih.gov/pubmed/34127714
http://dx.doi.org/10.1038/s41598-021-91792-1

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