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A genome-wide portrait of pervasive drug contaminants
Using a validated yeast chemogenomic platform, we characterized the genome-wide effects of several pharmaceutical contaminants, including three N-nitrosamines (NDMA, NDEA and NMBA), two related compounds (DMF and 4NQO) and several of their metabolites. A collection of 4800 non-essential homozygous d...
Autores principales: | Ogbede, Joseph Uche, Giaever, Guri, Nislow, Corey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203678/ https://www.ncbi.nlm.nih.gov/pubmed/34127714 http://dx.doi.org/10.1038/s41598-021-91792-1 |
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